Baclofen acts as a receptor agonist for which neurotransmitter?

Baclofen acts as a receptor agonist for GABA (gamma-aminobutyric acid), which is an important inhibitory neurotransmitter in the central nervous system. When baclofen is administered, it binds to GABA-B receptors, leading to decreased neuronal excitability. This action results in muscle relaxation and has been found to be beneficial in the treatment of spasticity, certain types of pain, and alcohol use disorders.

The role of GABA is crucial as it helps regulate anxiety, stress, and muscle tone, among other functions. By stimulating GABA-B receptors, baclofen can help mitigate withdrawal symptoms in individuals with alcohol dependence, making it a useful tool within addiction treatment. Understanding the relationship between baclofen and GABA can aid healthcare professionals in managing withdrawal symptoms and planning effective treatment strategies for patients with substance use disorders.