What is the recommended first-line treatment for acute mania?

Neuroleptics, also known as antipsychotics, are recognized as the recommended first-line treatment for acute mania. This class of medications is effective in quickly stabilizing mood and controlling symptoms such as agitation, hyperactivity, and psychosis that can occur during manic episodes. They work by blocking dopamine receptors in the brain, which helps to alleviate manic symptoms and promote a more stable emotional state.

While antidepressants and stimulants may have their roles in managing mood disorders, they can exacerbate manic symptoms if used alone or as initial treatments. Electroconvulsive therapy (ECT) is typically reserved for severe cases where other treatments have failed or when rapid response is needed due to the severity of the symptoms. Thus, neuroleptics are the most appropriate first-line intervention for managing acute mania effectively and safely.