Which antipsychotic medication is known to potentially cause transaminase elevation?

Olanzapine is recognized for its potential to cause elevations in transaminase levels. This side effect is particularly significant as it indicates potential liver issues, necessitating periodic liver function monitoring in patients receiving this medication. Elevated transaminases can reflect liver injury, which may be important to catch early in order to prevent more serious liver complications.

In clinical practice, it's crucial to assess the patient’s liver function regularly if they are on olanzapine, especially if they exhibit any symptoms such as jaundice, fatigue, or abdominal pain. This monitoring helps ensure safety and efficacy in the management of the patient's condition. The recognition of this side effect can lead to necessary adjustments in medication or additional investigations.