Withdrawal from which substance is often linked to psychiatric symptoms such as anxiety and depression?

Withdrawal from caffeine is indeed associated with various physical and psychological symptoms as the body adjusts to the absence of its stimulating effects. Common withdrawal symptoms can include headaches, fatigue, irritability, anxiety, and even depressive mood changes. Caffeine dependency can lead to a noticeable adjustment period when individuals significantly reduce or stop their intake.

In contrast, while nicotine withdrawal can result in mood disturbances and cravings, it is generally more closely associated with symptoms like irritability and cravings rather than the more significant psychiatric symptoms of anxiety and depression. Alcohol withdrawal is particularly severe and can lead to dangerous conditions such as delirium tremens, with severe anxiety, tremors, and even hallucinations, indicating a more pronounced effect on psychiatric symptoms than caffeine. Opioid withdrawal shares some psychological symptoms but is more characterized by physical discomfort, such as muscle aches and sweating, rather than predominantly psychiatric issues.

Thus, the recognition of caffeine withdrawal, primarily through its ability to induce anxiety and mood changes, distinguishes it in this context, making it a correct choice for this question.